Lysyl hydroxylases are transcription targets for GATA3 driving lung cancer cell metastasis

Metastasis associates with late stages of lung cancer progression and remains the main cause of patient death due to the lack of clinically effective therapeutics. Here we report that the transcription factor GATA3 and its co-factor FOG2 commonly promote the expression of the lysyl hydroxylase (LH)...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Zhang, Ting, Guo, Lixia, Wang, Yuanyuan, Yang, Yanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085355/
https://www.ncbi.nlm.nih.gov/pubmed/30093726
http://dx.doi.org/10.1038/s41598-018-30309-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085355/
https://www.ncbi.nlm.nih.gov/pubmed/30093726
http://dx.doi.org/10.1038/s41598-018-30309-9

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