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Lysyl hydroxylases are transcription targets for GATA3 driving lung cancer cell metastasis
Metastasis associates with late stages of lung cancer progression and remains the main cause of patient death due to the lack of clinically effective therapeutics. Here we report that the transcription factor GATA3 and its co-factor FOG2 commonly promote the expression of the lysyl hydroxylase (LH)...
Autores principales: | Liu, Wei, Zhang, Ting, Guo, Lixia, Wang, Yuanyuan, Yang, Yanan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085355/ https://www.ncbi.nlm.nih.gov/pubmed/30093726 http://dx.doi.org/10.1038/s41598-018-30309-9 |
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