Dysregulation in Actin Cytoskeletal Organization Drives Increased Stiffness and Migratory Persistence in Polyploidal Giant Cancer Cells

Polyploidal giant cancer cells (PGCCs) have been observed by pathologists in patient tumor samples and are especially prominent in late stage, high grade disease or after chemotherapy. However, they are often overlooked due to their apparent dormancy. Recent research has shown PGCCs to be chemoresis...

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Detalles Bibliográficos
Autores principales: Xuan, Botai, Ghosh, Deepraj, Cheney, Emily M., Clifton, Elizabeth M., Dawson, Michelle R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085392/
https://www.ncbi.nlm.nih.gov/pubmed/30093656
http://dx.doi.org/10.1038/s41598-018-29817-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085392/
https://www.ncbi.nlm.nih.gov/pubmed/30093656
http://dx.doi.org/10.1038/s41598-018-29817-5

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