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Modeling the Metabolic State of Mycobacterium tuberculosis Upon Infection

Genome-scale metabolic models of Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, have been envisioned as a platform for drug discovery. By systematically probing the networks that underpin such models, the reactions that are essential for Mtb are identified. A majority of thes...

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Detalles Bibliográficos
Autores principales: Rienksma, Rienk A., Schaap, Peter J., Martins dos Santos, Vitor A. P., Suarez-Diez, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085482/
https://www.ncbi.nlm.nih.gov/pubmed/30123778
http://dx.doi.org/10.3389/fcimb.2018.00264