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A Systems-Level Analysis Reveals Circadian Regulation of Splicing in Colorectal Cancer

Accumulating evidence points to a significant role of the circadian clock in the regulation of splicing in various organisms, including mammals. Both dysregulated circadian rhythms and aberrant pre-mRNA splicing are frequently implicated in human disease, in particular in cancer. To investigate the...

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Detalles Bibliográficos
Autores principales: El-Athman, Rukeia, Fuhr, Luise, Relógio, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085510/
https://www.ncbi.nlm.nih.gov/pubmed/29936137
http://dx.doi.org/10.1016/j.ebiom.2018.06.012