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A Nucleolar Stress–Specific p53–miR-101 Molecular Circuit Functions as an Intrinsic Tumor-Suppressor Network

BACKGROUND: Activation of intrinsic p53 tumor-suppressor (TS) pathways is an important principle underlying cancer chemotherapy. It is necessary to elucidate the precise regulatory mechanisms of these networks to create new treatment strategies. METHODS: Comprehensive analyses were carried out by mi...

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Detalles Bibliográficos
Autores principales: Fujiwara, Yuko, Saito, Motonobu, Robles, Ana I., Nishida, Momoyo, Takeshita, Fumitaka, Watanabe, Masatoshi, Ochiya, Takahiro, Yokota, Jun, Kohno, Takashi, Harris, Curtis C., Tsuchiya, Naoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085539/
https://www.ncbi.nlm.nih.gov/pubmed/30049386
http://dx.doi.org/10.1016/j.ebiom.2018.06.031