The Circadian Clock Regulates Metabolic Phenotype Rewiring Via HKDC1 and Modulates Tumor Progression and Drug Response in Colorectal Cancer

An endogenous molecular clockwork drives various cellular pathways including metabolism and the cell cycle. Its dysregulation is able to prompt pathological phenotypes including cancer. Besides dramatic metabolic alterations, cancer cells display severe changes in the clock phenotype with likely con...

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Detalles Bibliográficos
Autores principales: Fuhr, Luise, El-Athman, Rukeia, Scrima, Rosella, Cela, Olga, Carbone, Annalucia, Knoop, Henning, Li, Yin, Hoffmann, Karen, Laukkanen, Mikko O., Corcione, Francesco, Steuer, Ralf, Meyer, Thomas F., Mazzoccoli, Gianluigi, Capitanio, Nazzareno, Relógio, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085544/
https://www.ncbi.nlm.nih.gov/pubmed/30005951
http://dx.doi.org/10.1016/j.ebiom.2018.07.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085544/
https://www.ncbi.nlm.nih.gov/pubmed/30005951
http://dx.doi.org/10.1016/j.ebiom.2018.07.002

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