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Engineered Kidney Tubules for Modeling Patient-Specific Diseases and Drug Discovery
The lack of engineering systems able to faithfully reproduce complex kidney structures in vitro has made it difficult to efficiently model kidney diseases and development. Using polydimethylsiloxane (PDMS) scaffolds and a kidney-derived cell line we developed a system to rapidly engineer custom-made...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085557/ https://www.ncbi.nlm.nih.gov/pubmed/30049385 http://dx.doi.org/10.1016/j.ebiom.2018.06.005 |