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Engineered Kidney Tubules for Modeling Patient-Specific Diseases and Drug Discovery

The lack of engineering systems able to faithfully reproduce complex kidney structures in vitro has made it difficult to efficiently model kidney diseases and development. Using polydimethylsiloxane (PDMS) scaffolds and a kidney-derived cell line we developed a system to rapidly engineer custom-made...

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Detalles Bibliográficos
Autores principales: Benedetti, Valentina, Brizi, Valerio, Guida, Patrizia, Tomasoni, Susanna, Ciampi, Osele, Angeli, Elena, Valbusa, Ugo, Benigni, Ariela, Remuzzi, Giuseppe, Xinaris, Christodoulos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085557/
https://www.ncbi.nlm.nih.gov/pubmed/30049385
http://dx.doi.org/10.1016/j.ebiom.2018.06.005