Cargando…
Engineered Kidney Tubules for Modeling Patient-Specific Diseases and Drug Discovery
The lack of engineering systems able to faithfully reproduce complex kidney structures in vitro has made it difficult to efficiently model kidney diseases and development. Using polydimethylsiloxane (PDMS) scaffolds and a kidney-derived cell line we developed a system to rapidly engineer custom-made...
Autores principales: | Benedetti, Valentina, Brizi, Valerio, Guida, Patrizia, Tomasoni, Susanna, Ciampi, Osele, Angeli, Elena, Valbusa, Ugo, Benigni, Ariela, Remuzzi, Giuseppe, Xinaris, Christodoulos |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085557/ https://www.ncbi.nlm.nih.gov/pubmed/30049385 http://dx.doi.org/10.1016/j.ebiom.2018.06.005 |
Ejemplares similares
-
Generation of functional podocytes from human induced pluripotent stem cells
por: Ciampi, Osele, et al.
Publicado: (2016) -
Renal progenitors derived from human iPSCs engraft and restore function in a mouse model of acute kidney injury
por: Imberti, Barbara, et al.
Publicado: (2015) -
Engineering the vasculature of decellularized rat kidney scaffolds using human induced pluripotent stem cell-derived endothelial cells
por: Ciampi, Osele, et al.
Publicado: (2019) -
Unravelling the Role of PAX2 Mutation in Human Focal Segmental Glomerulosclerosis
por: Longaretti, Lorena, et al.
Publicado: (2021) -
Generation of two isogenic iPS cell lines (IRFMNi002-A and IRFMNi002-B) from a patient affected by Focal Segmental Glomerulosclerosis carrying a heterozygous c.565G>A mutation in PAX2 gene
por: Ciampi, Osele, et al.
Publicado: (2018)