The notch pathway promotes NF-κB activation through Asb2 in T cell acute lymphoblastic leukemia cells

BACKGROUND: Oncogenic Notch1 is known to activate the NF-κB pathway in T cell acute lymphoblastic leukemia (T-ALL) and to up-regulate the transcription of Asb2α, a specificity factor for an E3 ubiquitin ligase complex that plays an important role in hematopoietic differentiation. Therefore, we hypot...

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Detalles Bibliográficos
Autores principales: Wu, Wei, Nie, Li, Zhang, Li, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085606/
https://www.ncbi.nlm.nih.gov/pubmed/30116272
http://dx.doi.org/10.1186/s11658-018-0102-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085606/
https://www.ncbi.nlm.nih.gov/pubmed/30116272
http://dx.doi.org/10.1186/s11658-018-0102-4

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