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Histone demethylase JARID1B/KDM5B promotes aggressiveness of non-small cell lung cancer and serves as a good prognostic predictor

BACKGROUND: Lung cancer is the leading cause of cancer death worldwide. Recently, epigenetic dysregulation has been known to promote tumor progression and therefore may be a therapeutic target for anticancer therapy. JARID1B, a member of histone demethylases, has been found to be related to tumorige...

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Detalles Bibliográficos
Autores principales: Kuo, Kuang-Tai, Huang, Wen-Chien, Bamodu, Oluwaseun Adebayo, Lee, Wei-Hwa, Wang, Chun-Hua, Hsiao, M., Wang, Liang-Shun, Yeh, Chi-Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085612/
https://www.ncbi.nlm.nih.gov/pubmed/30092824
http://dx.doi.org/10.1186/s13148-018-0533-9