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Exploring the biological functional mechanism of the HMGB1/TLR4/MD-2 complex by surface plasmon resonance
BACKGROUND: High Mobility Group Box 1 (HMGB1) was first identified as a nonhistone chromatin-binding protein that functions as a pro-inflammatory cytokine and a Damage-Associated Molecular Pattern molecule when released from necrotic cells or activated leukocytes. HMGB1 consists of two structurally...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085627/ https://www.ncbi.nlm.nih.gov/pubmed/30134799 http://dx.doi.org/10.1186/s10020-018-0023-8 |