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Specific methionine oxidation of cytochrome c in complexes with zwitterionic lipids by hydrogen peroxide: potential implications for apoptosis

Cytochrome c (Cyt-c) has been previously shown to participate in cardiolipin (CL) oxidation and, therefore, in mitochondrial membrane permeabilization during the early events of apoptosis. The gain in this function has been ascribed to specific CL/Cyt-c interactions. Here we report that the cationic...

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Detalles Bibliográficos
Autores principales: Capdevila, Daiana A., Marmisollé, Waldemar A., Tomasina, Florencia, Demicheli, Verónica, Portela, Magdalena, Radi, Rafael, Murgida, Daniel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085654/
https://www.ncbi.nlm.nih.gov/pubmed/30154994
http://dx.doi.org/10.1039/c4sc02181a