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Sotetsuflavone inhibits proliferation and induces apoptosis of A549 cells through ROS-mediated mitochondrial-dependent pathway

BACKGROUND: Sotetsuflavone is isolated from Cycas revoluta Thunb., which has biological activity against tumors. However, the anti-proliferative effects of sotetsuflavone on A549 cells and its mechanism are not fully elucidated. METHODS: This study investigated the mechanisms of growth inhibition, c...

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Detalles Bibliográficos
Autores principales: Wang, Shaohui, Hu, Yanlan, Yan, Yu, Cheng, Zhekang, Liu, Tongxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085663/
https://www.ncbi.nlm.nih.gov/pubmed/30092797
http://dx.doi.org/10.1186/s12906-018-2300-z