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Epigenetic modification of mesenchymal stromal cells enhances their suppressive effects on the Th17 responses of cells from rheumatoid arthritis patients

BACKGROUND: The aim of this study was to investigate if epigenetically modified human mesenchymal stromal cells (hMSCs) can regulate the Th17-related immune responses. METHODS: We tested epigenetic drug combinations at various doses and selected the four combinations that resulted in maximal interle...

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Detalles Bibliográficos
Autores principales: Kim, Kyoung-Woon, Kim, Hye Joung, Kim, Bo-Mi, Kwon, Yong-Rim, Kim, Hae-Rim, Kim, Yoo-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085688/
https://www.ncbi.nlm.nih.gov/pubmed/30092847
http://dx.doi.org/10.1186/s13287-018-0948-4