Cargando…
Epigenetic modification of mesenchymal stromal cells enhances their suppressive effects on the Th17 responses of cells from rheumatoid arthritis patients
BACKGROUND: The aim of this study was to investigate if epigenetically modified human mesenchymal stromal cells (hMSCs) can regulate the Th17-related immune responses. METHODS: We tested epigenetic drug combinations at various doses and selected the four combinations that resulted in maximal interle...
Autores principales: | Kim, Kyoung-Woon, Kim, Hye Joung, Kim, Bo-Mi, Kwon, Yong-Rim, Kim, Hae-Rim, Kim, Yoo-Jin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085688/ https://www.ncbi.nlm.nih.gov/pubmed/30092847 http://dx.doi.org/10.1186/s13287-018-0948-4 |
Ejemplares similares
-
Roles of mast cells in rheumatoid arthritis
por: Min, Hong Ki, et al.
Publicado: (2020) -
Enhanced differentiation of mesenchymal stromal cells by three-dimensional culture and azacitidine
por: Bae, Yoo-Jin, et al.
Publicado: (2017) -
IL-18 binding protein suppresses IL-17-induced osteoclastogenesis and rectifies type 17 helper T cell / regulatory T cell imbalance in rheumatoid arthritis
por: Min, Hong Ki, et al.
Publicado: (2021) -
Macrophage migration inhibitory factor: a potential therapeutic target for rheumatoid arthritis
por: Kim, Kyoung-Woon, et al.
Publicado: (2016) -
N-acetyl-l-cysteine controls osteoclastogenesis through regulating Th17 differentiation and RANKL in rheumatoid arthritis
por: Kim, Hae-Rim, et al.
Publicado: (2019)