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Combination statin and chemotherapy inhibits proliferation and cytotoxicity of an aggressive natural killer cell leukemia

BACKGROUND: Aggressive natural killer cell leukemia is a devastating disease, with an average patient survival time of less than 2 months following diagnosis. Due to P-glycoprotein-mediated resistance of the tumor cells most forms of chemotherapy are of limited efficacy, therefore new treatment stra...

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Detalles Bibliográficos
Autores principales: Henslee, Austin B., Steele, Timothy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085711/
https://www.ncbi.nlm.nih.gov/pubmed/30116531
http://dx.doi.org/10.1186/s40364-018-0140-0