Cargando…
Homeobox oncogene activation by pan-cancer DNA hypermethylation
BACKGROUND: Cancers have long been recognized to be not only genetically but also epigenetically distinct from their tissues of origin. Although genetic alterations underlying oncogene upregulation have been well studied, to what extent epigenetic mechanisms, such as DNA methylation, can also induce...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085761/ https://www.ncbi.nlm.nih.gov/pubmed/30097071 http://dx.doi.org/10.1186/s13059-018-1492-3 |