Homeobox oncogene activation by pan-cancer DNA hypermethylation

BACKGROUND: Cancers have long been recognized to be not only genetically but also epigenetically distinct from their tissues of origin. Although genetic alterations underlying oncogene upregulation have been well studied, to what extent epigenetic mechanisms, such as DNA methylation, can also induce...

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Detalles Bibliográficos
Autores principales: Su, Jianzhong, Huang, Yung-Hsin, Cui, Xiaodong, Wang, Xinyu, Zhang, Xiaotian, Lei, Yong, Xu, Jianfeng, Lin, Xueqiu, Chen, Kaifu, Lv, Jie, Goodell, Margaret A., Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085761/
https://www.ncbi.nlm.nih.gov/pubmed/30097071
http://dx.doi.org/10.1186/s13059-018-1492-3

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