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ChromTime: modeling spatio-temporal dynamics of chromatin marks

To model spatial changes of chromatin mark peaks over time we develop and apply ChromTime, a computational method that predicts peaks to be either expanding, contracting, or holding steady between time points. Predicted expanding and contracting peaks can mark regulatory regions associated with tran...

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Detalles Bibliográficos
Autores principales: Fiziev, Petko, Ernst, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085762/
https://www.ncbi.nlm.nih.gov/pubmed/30097049
http://dx.doi.org/10.1186/s13059-018-1485-2