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Maternal gene Ooep may participate in homologous recombination-mediated DNA double-strand break repair in mouse oocytes

DNA damage in oocytes can cause infertility and birth defects. DNA double-strand breaks (DSBs) are highly deleterious and can substantially impair genome integrity. Homologous recombination (HR)-mediated DNA DSB repair plays dominant roles in safeguarding oocyte quantity and quality. However, little...

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Detalles Bibliográficos
Autores principales: He, Da-Jian, Wang, Lin, Zhang, Zhi-Bi, Guo, Kun, Li, Jing-Zheng, He, Xie-Chao, Cui, Qing-Hua, Zheng, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085769/
https://www.ncbi.nlm.nih.gov/pubmed/29955025
http://dx.doi.org/10.24272/j.issn.2095-8137.2018.067