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Maternal gene Ooep may participate in homologous recombination-mediated DNA double-strand break repair in mouse oocytes
DNA damage in oocytes can cause infertility and birth defects. DNA double-strand breaks (DSBs) are highly deleterious and can substantially impair genome integrity. Homologous recombination (HR)-mediated DNA DSB repair plays dominant roles in safeguarding oocyte quantity and quality. However, little...
Autores principales: | He, Da-Jian, Wang, Lin, Zhang, Zhi-Bi, Guo, Kun, Li, Jing-Zheng, He, Xie-Chao, Cui, Qing-Hua, Zheng, Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Science Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085769/ https://www.ncbi.nlm.nih.gov/pubmed/29955025 http://dx.doi.org/10.24272/j.issn.2095-8137.2018.067 |
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