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Comparison of Two Genotyping Methods for Distinguishing Recrudescence from Reinfection in Antimalarial Drug Efficacy/Effectiveness Trials

Genotyping of allelic variants of Plasmodium falciparum merozoite surface proteins 1 and 2 (msp-1 and msp-2), and the glutamate-rich protein is the gold standard for distinguishing reinfections from recrudescences in antimalarial drug trials. We compared performance of the recently developed 24-sing...

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Detalles Bibliográficos
Autores principales: Fulakeza, Joseph R. M., Banda, Rachel L., Lipenga, Trancizeo R., Terlouw, Dianne J., Nkhoma, Standwell C., Hodel, Eva Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085787/
https://www.ncbi.nlm.nih.gov/pubmed/29785925
http://dx.doi.org/10.4269/ajtmh.18-0002