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The prionlike domain of FUS is multiphosphorylated following DNA damage without altering nuclear localization
FUS (fused in sarcoma) is an abundant, predominantly nuclear protein involved in RNA processing. Under various conditions, FUS functionally associates with RNA and other macromolecules to form distinct, reversible phase-separated liquid structures. Persistence of the phase-separated state and increa...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085830/ https://www.ncbi.nlm.nih.gov/pubmed/29897835 http://dx.doi.org/10.1091/mbc.E17-12-0735 |