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Mutational Profile of Papillary Thyroid Carcinoma in an Endemic Goiter Region of North India

INTRODUCTION: Mitogen activated protein kinase (MAPK) pathway is regularly altered in papillary thyroid carcinomas (PTCs). Serine/threonine-protein kinase B-Raf (BRAF) V600E mutations were observed very frequently in PTC along with less frequent rat sarcoma (RAS) and rearranged during transfection (...

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Detalles Bibliográficos
Autores principales: George, Nelson, Agarwal, Amit, Kumari, Niraj, Agarwal, Sarita, Krisnani, Narendra, Gupta, Sushil Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085952/
https://www.ncbi.nlm.nih.gov/pubmed/30148098
http://dx.doi.org/10.4103/ijem.IJEM_441_17