Elucidating the Inhibitory Potential of Designed Peptides Against Amyloid Fibrillation and Amyloid Associated Cytotoxicity

Inhibition of fibrillation process and disaggregation of mature fibrils using small peptide are the promising remedial strategies to combat neurodegenerative diseases. However, designing peptide-based drugs to target β-sheet-rich amyloid has been a major challenge. The current work describes, for th...

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Detalles Bibliográficos
Autores principales: Siddiqi, Mohammad K., Alam, Parvez, Iqbal, Tabish, Majid, Nabeela, Malik, Sadia, Nusrat, Saima, Alam, Aftab, Ajmal, Mohd R., Uversky, Vladimir N., Khan, Rizwan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085999/
https://www.ncbi.nlm.nih.gov/pubmed/30123793
http://dx.doi.org/10.3389/fchem.2018.00311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085999/
https://www.ncbi.nlm.nih.gov/pubmed/30123793
http://dx.doi.org/10.3389/fchem.2018.00311

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