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The Involvement of Aβ42 and Tau in Nucleolar and Protein Synthesis Machinery Dysfunction

Alzheimer’s disease (AD) is the most common form of dementia and is distinguished from other dementias by observation of extracellular Amyloid-β (Aβ) plaques and intracellular neurofibrillary tangles, comprised of fibrils of Aβ and tau protein, respectively. At early stages, AD is characterized by m...

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Detalles Bibliográficos
Autores principales: Maina, Mahmoud B., Bailey, Laura J., Doherty, Aidan J., Serpell, Louise C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086011/
https://www.ncbi.nlm.nih.gov/pubmed/30123109
http://dx.doi.org/10.3389/fncel.2018.00220