Geniposide Alleviates Isoproterenol-Induced Cardiac Fibrosis Partially via SIRT1 Activation in vivo and in vitro

Objective: Geniposide (GE) is a major component in the fruit of Gardenia jasminoides Ellis. Oxidative stress, endoplasmic reticulum (ER) stress, and canonical Smad3 pathway are implicated in the pathogenesis of cardiac fibrosis. We aim to investigate the protective roles of GE in isoproterenol (ISO)...

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Detalles Bibliográficos
Autores principales: Li, Ning, Zhou, Heng, Ma, Zhen-Guo, Zhu, Jin-Xiu, Liu, Chen, Song, Peng, Kong, Chun-Yan, Wu, Hai-Ming, Deng, Wei, Tang, Qi-Zhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086014/
https://www.ncbi.nlm.nih.gov/pubmed/30123131
http://dx.doi.org/10.3389/fphar.2018.00854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086014/
https://www.ncbi.nlm.nih.gov/pubmed/30123131
http://dx.doi.org/10.3389/fphar.2018.00854

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