Knockdown of PAICS inhibits malignant proliferation of human breast cancer cell lines

BACKGROUND: Phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS), an enzyme required for de novo purine biosynthesis, is associated with and involved in tumorigenesis. This study aimed to evaluate the role of PAICS in human breast cancer, which...

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Detalles Bibliográficos
Autores principales: Meng, Minjun, Chen, Yanling, Jia, Jianbo, Li, Lianghui, Yang, Sumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086025/
https://www.ncbi.nlm.nih.gov/pubmed/30097015
http://dx.doi.org/10.1186/s40659-018-0172-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086025/
https://www.ncbi.nlm.nih.gov/pubmed/30097015
http://dx.doi.org/10.1186/s40659-018-0172-9

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