miREM: an expectation-maximization approach for prioritizing miRNAs associated with gene-set

BACKGROUND: The knowledge of miRNAs regulating the expression of sets of mRNAs has led to novel insights into numerous and diverse cellular mechanisms. While a single miRNA may regulate many genes, one gene can be regulated by multiple miRNAs, presenting a complex relationship to model for accurate...

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Detalles Bibliográficos
Autores principales: Abdul Hadi, Luqman Hakim, Xuan Lin, Quy Xiao, Minh, Tri Tran, Loh, Marie, Ng, Hong Kiat, Salim, Agus, Soong, Richie, Benoukraf, Touati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086043/
https://www.ncbi.nlm.nih.gov/pubmed/30097004
http://dx.doi.org/10.1186/s12859-018-2292-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086043/
https://www.ncbi.nlm.nih.gov/pubmed/30097004
http://dx.doi.org/10.1186/s12859-018-2292-1

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