Biological and clinical influences of NPM1 in acute myeloid leukemia patients with DNMT3A mutations

PURPOSE: DNMT3A and NPM1 mutations are known to impact the prognosis of acute myeloid leukemia (AML). DNMT3A mutations are negative prognostic factors, while NPM1 mutations are low-risk factors and inclined to concurrently appear with DNMT3A mutations. In this study, we aimed to find out how NPM1 mu...

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Detalles Bibliográficos
Autores principales: Yang, Xinrui, Shi, Jinlong, Zhang, Xinpei, Zhang, Gaoqi, Zhang, Jilei, Yang, Siyuan, Wang, Jing, Ke, Xiaoyan, Fu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086113/
https://www.ncbi.nlm.nih.gov/pubmed/30122998
http://dx.doi.org/10.2147/CMAR.S166714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086113/
https://www.ncbi.nlm.nih.gov/pubmed/30122998
http://dx.doi.org/10.2147/CMAR.S166714

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