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Biological and clinical influences of NPM1 in acute myeloid leukemia patients with DNMT3A mutations
PURPOSE: DNMT3A and NPM1 mutations are known to impact the prognosis of acute myeloid leukemia (AML). DNMT3A mutations are negative prognostic factors, while NPM1 mutations are low-risk factors and inclined to concurrently appear with DNMT3A mutations. In this study, we aimed to find out how NPM1 mu...
Autores principales: | Yang, Xinrui, Shi, Jinlong, Zhang, Xinpei, Zhang, Gaoqi, Zhang, Jilei, Yang, Siyuan, Wang, Jing, Ke, Xiaoyan, Fu, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086113/ https://www.ncbi.nlm.nih.gov/pubmed/30122998 http://dx.doi.org/10.2147/CMAR.S166714 |
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