Replacing the 238th aspartic acid with an arginine impaired the oligomerization activity and inflammation-inducing property of pyolysin

Trueperella pyogenes (T. pyogenes) is an important opportunistic pathogen. Pyolysin (PLO) importantly contributes to the pathogenicity of T. pyogenes. However, the relationship between the structure and function and the virulence of PLO is not well documented. In the current study, recombinant PLO (...

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Detalles Bibliográficos
Autores principales: Zhang, Wenlong, Wang, Haili, Wang, Bing, Zhang, Yue, Hu, Yunhao, Ma, Bo, Wang, Junwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086297/
https://www.ncbi.nlm.nih.gov/pubmed/30067143
http://dx.doi.org/10.1080/21505594.2018.1491256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086297/
https://www.ncbi.nlm.nih.gov/pubmed/30067143
http://dx.doi.org/10.1080/21505594.2018.1491256

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