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Replacing the 238th aspartic acid with an arginine impaired the oligomerization activity and inflammation-inducing property of pyolysin
Trueperella pyogenes (T. pyogenes) is an important opportunistic pathogen. Pyolysin (PLO) importantly contributes to the pathogenicity of T. pyogenes. However, the relationship between the structure and function and the virulence of PLO is not well documented. In the current study, recombinant PLO (...
Autores principales: | Zhang, Wenlong, Wang, Haili, Wang, Bing, Zhang, Yue, Hu, Yunhao, Ma, Bo, Wang, Junwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086297/ https://www.ncbi.nlm.nih.gov/pubmed/30067143 http://dx.doi.org/10.1080/21505594.2018.1491256 |
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