Defective germline reprogramming rewires the spermatogonial transcriptome

Defective germline reprogramming in Miwi2- and Dnmt3l-deficient mice results in the failure to reestablish transposon silencing, meiotic arrest and progressive loss of spermatogonia. Here we sought to understand the molecular basis for this spermatogonial dysfunction. Through a combination of imagin...

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Detalles Bibliográficos
Autores principales: Vasiliauskaitė, Lina, Berrens, Rebecca V, Ivanova, Ivayla, Carrieri, Claudia, Reik, Wolf, Enright, Anton J, O’Carroll, Dónal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086329/
https://www.ncbi.nlm.nih.gov/pubmed/29728652
http://dx.doi.org/10.1038/s41594-018-0058-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086329/
https://www.ncbi.nlm.nih.gov/pubmed/29728652
http://dx.doi.org/10.1038/s41594-018-0058-0

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