Preserved cardiac function by vinculin enhances glucose oxidation and extends health- and life-span

Despite limited regenerative capacity as we age, cardiomyocytes maintain their function in part through compensatory mechanisms, e.g., Vinculin reinforcement of intercalated discs in aged organisms. This mechanism, which is conserved from flies to non-human primates, creates a more crystalline sarco...

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Detalles Bibliográficos
Autores principales: Sessions, Ayla O., Min, Peter, Cordes, Thekla, Weickert, Barry J., Divakaruni, Ajit S., Murphy, Anne N., Metallo, Christian M., Engler, Adam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086353/
https://www.ncbi.nlm.nih.gov/pubmed/30105314
http://dx.doi.org/10.1063/1.5019592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086353/
https://www.ncbi.nlm.nih.gov/pubmed/30105314
http://dx.doi.org/10.1063/1.5019592

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