Cargando…
LSD1 mediated changes in the local redox environment during the DNA damage response
The redox state of the cell can be affected by many cellular conditions. In this study we show that detectable reactive oxygen species (ROS) are also generated in response to DNA damage by the chromatin remodeling factor and monoamine oxidase LSD1/KDM1A. This raised the possibility that the localize...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086436/ https://www.ncbi.nlm.nih.gov/pubmed/30096172 http://dx.doi.org/10.1371/journal.pone.0201907 |