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LSD1 mediated changes in the local redox environment during the DNA damage response

The redox state of the cell can be affected by many cellular conditions. In this study we show that detectable reactive oxygen species (ROS) are also generated in response to DNA damage by the chromatin remodeling factor and monoamine oxidase LSD1/KDM1A. This raised the possibility that the localize...

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Detalles Bibliográficos
Autores principales: Duquette, Michelle L., Kim, Justine, Shi, Linda Z., Berns, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086436/
https://www.ncbi.nlm.nih.gov/pubmed/30096172
http://dx.doi.org/10.1371/journal.pone.0201907