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Upregulation of PD-L1 expression by resveratrol and piceatannol in breast and colorectal cancer cells occurs via HDAC3/p300-mediated NF-κB signaling

Programmed cell death ligand 1 (PD-L1) expressed in cancer cells interacting with its receptor programmed cell death 1 (PD-1) expressed in immune cells represents a regulatory axis linked to the suppression and evasion of host immune functions. The blockade of PD-1/PD-L1 interaction using monoclonal...

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Detalles Bibliográficos
Autores principales: Lucas, Justin, Hsieh, Tze-Chen, Halicka, H. Dorota, Darzynkiewicz, Zbigniew, Wu, Joseph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086626/
https://www.ncbi.nlm.nih.gov/pubmed/30066852
http://dx.doi.org/10.3892/ijo.2018.4512