Membrane insertion of α-xenorhabdolysin in near-atomic detail

α-Xenorhabdolysins (Xax) are α-pore-forming toxins (α-PFT) that form 1–1.3 MDa large pore complexes to perforate the host cell membrane. PFTs are used by a variety of bacterial pathogens to attack host cells. Due to the lack of structural information, the molecular mechanism of action of Xax toxins...

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Detalles Bibliográficos
Autores principales: Schubert, Evelyn, Vetter, Ingrid R, Prumbaum, Daniel, Penczek, Pawel A, Raunser, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086661/
https://www.ncbi.nlm.nih.gov/pubmed/30010541
http://dx.doi.org/10.7554/eLife.38017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086661/
https://www.ncbi.nlm.nih.gov/pubmed/30010541
http://dx.doi.org/10.7554/eLife.38017

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