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Estimating the protein burden limit of yeast cells by measuring the expression limits of glycolytic proteins

The ultimate overexpression of a protein could cause growth defects, which are known as the protein burden. However, the expression limit at which the protein-burden effect is triggered is still unclear. To estimate this limit, we systematically measured the overexpression limits of glycolytic prote...

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Detalles Bibliográficos
Autores principales: Eguchi, Yuichi, Makanae, Koji, Hasunuma, Tomohisa, Ishibashi, Yuko, Kito, Keiji, Moriya, Hisao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086662/
https://www.ncbi.nlm.nih.gov/pubmed/30095406
http://dx.doi.org/10.7554/eLife.34595