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Soluble inflammatory mediators induce transcriptional re-organization that is independent of dna methylation changes in cultured human chorionic villous trophoblasts

The studies proposed here were undertaken to test the hypothesis that, under specific circumstances (e.g., a strong enough inflammatory stimulus), genes that are repressed at the maternal-fetal interface via DNA methylation might be de-methylated, allowing either a maternal immune response to the se...

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Detalles Bibliográficos
Autores principales: Jiang, Kaiyu, Wong, Laiping, Chen, Yanmin, Xing, Xiaoyun, Li, Daofeng, Wang, Ting, Jarvis, James N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086739/
https://www.ncbi.nlm.nih.gov/pubmed/29800761
http://dx.doi.org/10.1016/j.jri.2018.05.005