Cholesterol modulates acetylcholine receptor diffusion by tuning confinement sojourns and nanocluster stability

Translational motion of neurotransmitter receptors is key for determining receptor number at the synapse and hence, synaptic efficacy. We combine live-cell STORM superresolution microscopy of nicotinic acetylcholine receptor (nAChR) with single-particle tracking, mean-squared displacement (MSD), tur...

Descripción completa

Detalles Bibliográficos
Autores principales: Mosqueira, Alejo, Camino, Pablo A., Barrantes, Francisco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086833/
https://www.ncbi.nlm.nih.gov/pubmed/30097590
http://dx.doi.org/10.1038/s41598-018-30384-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086833/
https://www.ncbi.nlm.nih.gov/pubmed/30097590
http://dx.doi.org/10.1038/s41598-018-30384-y

Ejemplares similares