Circadian clock disruption by selective removal of endogenous carbon monoxide

Circadian rhythms are regulated by transcription-translation feedback loops (TTFL) of clock genes. Previous studies have demonstrated that core transcriptional factors, NPAS2 and CLOCK, in the TTFL can reversibly bind carbon monoxide (CO) in vitro. However, little is known about whether endogenous C...

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Detalles Bibliográficos
Autores principales: Minegishi, Saika, Sagami, Ikuko, Negi, Shigeru, Kano, Koji, Kitagishi, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086871/
https://www.ncbi.nlm.nih.gov/pubmed/30097595
http://dx.doi.org/10.1038/s41598-018-30425-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086871/
https://www.ncbi.nlm.nih.gov/pubmed/30097595
http://dx.doi.org/10.1038/s41598-018-30425-6

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