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Circadian clock disruption by selective removal of endogenous carbon monoxide
Circadian rhythms are regulated by transcription-translation feedback loops (TTFL) of clock genes. Previous studies have demonstrated that core transcriptional factors, NPAS2 and CLOCK, in the TTFL can reversibly bind carbon monoxide (CO) in vitro. However, little is known about whether endogenous C...
Autores principales: | Minegishi, Saika, Sagami, Ikuko, Negi, Shigeru, Kano, Koji, Kitagishi, Hiroaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086871/ https://www.ncbi.nlm.nih.gov/pubmed/30097595 http://dx.doi.org/10.1038/s41598-018-30425-6 |
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