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Single cell analysis reveals a biophysical aspect of collective cell-state transition in embryonic stem cell differentiation

In the stem cell research field, the molecular regulatory network used to define cellular states has been extensively studied, however, the general driving force guiding the collective state dynamics remains to be identified from biophysical aspects. Here we monitored the time-development of the cel...

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Detalles Bibliográficos
Autores principales: Okamoto, Kazuko, Germond, Arno, Fujita, Hideaki, Furusawa, Chikara, Okada, Yasushi, Watanabe, Tomonobu M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086879/
https://www.ncbi.nlm.nih.gov/pubmed/30097661
http://dx.doi.org/10.1038/s41598-018-30461-2