Adenosine Kinase couples sensing of cellular potassium depletion to purine metabolism

Adenosine Kinase (ADK) regulates the cellular levels of adenosine (ADO) by fine-tuning its metabolic clearance. The transfer of γ-phosphate from ATP to ADO by ADK involves regulation by the substrates and products, as well as by Mg(2+) and inorganic phosphate. Here we present new crystal structures...

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Detalles Bibliográficos
Autores principales: de Oliveira, Renata Rocha, Morales-Neto, Raphael, Rocco, Silvana Aparecida, Sforça, Maurício Luis, Polo, Carla Cristina, Tonoli, Celisa Caldana Costa, Mercaldi, Gustavo Fernando, Cordeiro, Artur Torres, Murakami, Mário Tyago, Franchini, Kleber Gomes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086891/
https://www.ncbi.nlm.nih.gov/pubmed/30097648
http://dx.doi.org/10.1038/s41598-018-30418-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086891/
https://www.ncbi.nlm.nih.gov/pubmed/30097648
http://dx.doi.org/10.1038/s41598-018-30418-5

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