Targeting Nucleotide Binding Domain of Multidrug Resistance-associated Protein-1 (MRP1) for the Reversal of Multi Drug Resistance in Cancer

Multidrug resistance (MDR) is the major cause, by which cancer cells expel the drugs out, developing a challenge against the current chemotherapeutic drugs regime. This mechanism is attributed to the over expression of ABC transporters like MRP1 on the surface of cells. Since nucleotide binding doma...

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Detalles Bibliográficos
Autores principales: Dhasmana, Divya, Singh, Ashutosh, Shukla, Rohit, Tripathi, Timir, Garg, Neha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086895/
https://www.ncbi.nlm.nih.gov/pubmed/30097643
http://dx.doi.org/10.1038/s41598-018-30420-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086895/
https://www.ncbi.nlm.nih.gov/pubmed/30097643
http://dx.doi.org/10.1038/s41598-018-30420-x

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