Enzyme-modified non-oxidized LDL (ELDL) induces human coronary artery smooth muscle cell transformation to a migratory and osteoblast-like phenotype

Enzyme modified non-oxidative LDL (ELDL) is effectively taken up by vascular smooth muscle cells (SMC) and mediates transition into foam cells and produces phenotypic changes in SMC function. Our data show that incubation of human coronary artery SMC (HCASMC) with low concentration of ELDL (10 μg/ml...

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Detalles Bibliográficos
Autores principales: Chellan, Bijoy, Rojas, Elizabeth, Zhang, Chunling, Hofmann Bowman, Marion A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086911/
https://www.ncbi.nlm.nih.gov/pubmed/30097618
http://dx.doi.org/10.1038/s41598-018-30073-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086911/
https://www.ncbi.nlm.nih.gov/pubmed/30097618
http://dx.doi.org/10.1038/s41598-018-30073-w

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