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Anti-CRISPR Phages Cooperate to Overcome CRISPR-Cas Immunity

Some phages encode anti-CRISPR (acr) genes, which antagonize bacterial CRISPR-Cas immune systems by binding components of its machinery, but it is less clear how deployment of these acr genes impacts phage replication and epidemiology. Here, we demonstrate that bacteria with CRISPR-Cas resistance ar...

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Detalles Bibliográficos
Autores principales: Landsberger, Mariann, Gandon, Sylvain, Meaden, Sean, Rollie, Clare, Chevallereau, Anne, Chabas, Hélène, Buckling, Angus, Westra, Edze R., van Houte, Stineke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086933/
https://www.ncbi.nlm.nih.gov/pubmed/30033365
http://dx.doi.org/10.1016/j.cell.2018.05.058