PHD3 Regulates p53 Protein Stability by Hydroxylating Proline 359

Cellular p53 protein levels are regulated by a ubiquitination/de-ubiquitination cycle that can target the protein for proteasomal destruction. The ubiquitination reaction is catalyzed by a multitude of ligases, whereas the removal of ubiquitin chains is mediated by two deubiquitinating enzymes (DUBs...

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Detalles Bibliográficos
Autores principales: Rodriguez, Javier, Herrero, Ana, Li, Shuijie, Rauch, Nora, Quintanilla, Andrea, Wynne, Kieran, Krstic, Aleksandar, Acosta, Juan Carlos, Taylor, Cormac, Schlisio, Susanne, von Kriegsheim, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088137/
https://www.ncbi.nlm.nih.gov/pubmed/30067985
http://dx.doi.org/10.1016/j.celrep.2018.06.108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088137/
https://www.ncbi.nlm.nih.gov/pubmed/30067985
http://dx.doi.org/10.1016/j.celrep.2018.06.108

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